Br J Ophthalmol 2001;85:214-218
( February )
Scientific correspondence
Indocyanine green angiography of the anterior segment in patients
undergoing strabismus surgery
Tin K J Chana b, Arthur L Rosenbauma, Rajesh Raoa, Steven D Schwartza, Pauline Santiagoa, Dennis Thayera
a Department of
Ophthalmology, University of California, Los Angeles, CA, USA, b Department
of Ophthalmology, Royal Hallamshire Hospital, University of Sheffield,
Sheffield, UK
Correspondence to: Arthur Rosenbaum, MD, Jules Stein Eye Institute, 100 Stein Plaza, UCLA,
Los Angeles, CA 90095-7002, USA
rosenbaum{at}jseint.jsei.ucla.edu
Accepted for publication 19 November 2000
BACKGROUND
Anterior
segment imaging using fluorescein angiography is only suitable in
lightly pigmented irides as the brown pigmentation of the iris masks
fluorescein transmission. Indocyanine green (ICG) angiography has
excellent penetration of pigment epithelium and, therefore, has
potential application in detecting perfusion changes of dark irides
after strabismus surgery.
METHODSA prospective
study was conducted on patients older than 15 years undergoing
strabismus surgery. A fundus camera was focused on the arteriolar tufts
of the pupillary margin and 50 mg of ICG (concentration of 12.5 mg/ml)
was given intravenously. Images were then obtained at 1 minute
intervals of 5 minutes' duration.
RESULTS45 patients
with a mean age of 54.6 years and a mean follow up period of 8.6 weeks
were studied. There were 23 patients in the primary surgery group, 11 in the secondary surgery group, and 11 in the staged group. Iris ICG
angiograms were successfully performed in all patients. No persistent
filling defect was detected in the primary and secondary horizontal
recti surgery groups or in the secondary or staged vertical and
combined vertical rectus groups 6-8 weeks postoperatively. 57% of
both primary vertical and combined vertical and horizontal groups
showed defects in the early postoperative phase. Only three cases
demonstrated late perfusion defects in this series.
CONCLUSIONICG can
detect iris perfusion changes in dark irides after strabismus surgery.
Iris reperfusion was achieved in the majority of the cases.
© 2001 by British Journal of Ophthalmology
