Br J Ophthalmol 2000;84:385-389
( April )
Analysis of variation in success rates in conjunctival
autografting for primary and recurrent pterygium
S E Tia, S P Cheea, K B G Dearb, D T H Tana c
a Singapore National
Eye Centre, Singapore, b Department of Statistics, University of
Newcastle, Australia, c National
University of Singapore
Correspondence to: Ti Seng-Ei, MD, Singapore National Eye Centre, 11 Third
Hospital Avenue, Singapore 168751
Accepted for publication 5 November 1999
AIMS To evaluate the
success rates of conjunctival autografting for primary and recurrent
pterygium performed in a tertiary ophthalmic centre.
METHODS The outcome of
139 cases with primary pterygia and 64 cases with recurrent pterygia
who underwent excision with conjunctival autografting was
retrospectively reviewed. Outcome was evaluated in terms of recurrence
of pterygia onto the cornea. The recurrence rates were determined using
Weibull survival functions, in a mixture model that included a
component allowing for cure. The suitability of this model was verified
using Turnbull's non-parametric method for interval censored data
(1974). Estimated recurrence free probabilities were based on the
fitted Weibull survival curves.
RESULTS Mean follow up
was 8.4 months in the primary group, and 9.5 months for the recurrent
group. 29 out of 139 cases of primary pterygia recurred (20.8%) while
20 out of 64 cases in the recurrent group (31.2%) recurred. Recurrence
rates varied widely among surgeons, ranging from 5% to 82%.
Recurrence rates were inversely related to previous experience in
performing conjunctival grafting. The recurrence free probability was
84% at 3 months, 73% at 1 year for primary pterygia, and 80% at 3 months, 67% at 1 year for recurrent pterygia. There was no statistical
difference in recurrence rates between primary and recurrent groups (p=
0.80).
CONCLUSION The success
of conjunctival autografting for pterygium in this series varies
widely, and may be related to a significant learning curve or differing
surgical techniques for this procedure. This may account for the wide
variation in reported success of this procedure in the ophthalmic literature.
© 2000 by British Journal of Ophthalmology
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