Br J Ophthalmol 2000;84:259-263
( March )
Prospective surveillance of sympathetic ophthalmia in the UK and
Republic of Ireland
Dara J Kilmartin, Andrew D Dick, John V Forrester
Department of
Ophthalmology, University of Aberdeen Medical School, Foresterhill,
Aberdeen AB25 2ZD
Correspondence to: Mr Dara J Kilmartin
Accepted for publication 8 November 1999
AIMS To establish
current epidemiological data, risks, and interventional outcomes of
newly diagnosed sympathetic ophthalmia (SO).
METHODS Prospective
surveillance took place of all permanently employed ophthalmologists in
the UK and Republic of Ireland by a monthly reporting card through the
British Ophthalmological Surveillance Unit. Case ascertainment was made
of newly diagnosed SO from July 1997 and questionnaire data were
returned at baseline, 6 months, and 1 year after diagnosis.
RESULTS 23 patients
with newly diagnosed SO were recruited over 15 months, corresponding to
a minimum estimated incidence of 0.03/100 000. Baseline data were
available on 18 patients, in whom SO occurred after surgery in 11 patients, after retinal surgery alone in six patients, and after
accidental trauma in seven patients. 12 of the 16 patients with 1 year
follow up had a visual acuity of 6/12 or better. Good visual outcome
was related to prompt and adequate systemic immunosuppressive therapy.
CONCLUSIONS The
incidence of sympathetic ophthalmia is very low. The main current risk
is surgery, particularly retinal surgery, but visual prognosis is good
if early diagnosis is made and rapid, adequate immunotherapy is commenced.
© 2000 by British Journal of Ophthalmology
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