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Br J Ophthalmol 1999;83:29-32 ( January )

Immediate intraocular pressure response to selective laser trabeculoplasty

Paolo Lanzetta, Ugo Menchini, Gianni Virgili

Department of Ophthalmology, University of Udine, Udine, Italy

Correspondence to: Paolo Lanzetta, MD, Department of Ophthalmology, University of Udine, Viale Venezia, 410, 33100 Udine, Italy.

Accepted for publication 26 August 1998

BACKGROUND/AIMS---Selective laser trabeculoplasty targets the pigmented trabecular meshwork cells without damage to the trabecular meshwork architecture in vitro. A study was conducted in vivo of eight eyes with uncontrolled open angle glaucoma to ascertain the immediate intraocular response to selective laser trabeculoplasty.
METHODS---The trabecular meshwork of each eye was treated 360° with a frequency doubled Q-switched Nd:YAG laser. Intraocular pressure was measured 1, 2, 24 hours and 1, 4, 6 weeks after treatment.
RESULTS---The average preoperative intraocular pressure was 26.6 (SD 7) mm Hg (range 18-37). Two hours and 6 weeks respectively after selective trabeculoplasty intraocular pressure was reduced in all the eyes treated with an average fall of 10.6 (5.2) mm Hg or 39.9%. A pressure spike of 10 mm Hg verified in one eye 1 hour after treatment.
CONCLUSIONS---Selective laser trabeculoplasty decreased intraocular pressure by an amount similar to that achieved with standard trabeculoplasty. Additional study is needed to determine whether the beneficial effect is sustained over a longer period of follow up.

Keywords: laser trabeculoplasty, primary open angle glaucoma

© 1999 by British Journal of Ophthalmology


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