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Br J Ophthalmol 1998;82:1312-1315 ( November )

Intraocular lens implants and risk of endophthalmitis

J W B Bainbridge,a M Teimory,a H Tabandeh,a J F Kirwan,a R Dalton,a F Reid,b C K Rostrona

a Department of Ophthalmology, St George's Hospital, London SW17 0QT, b Department of Medical Statistics, St George's Hospital Medical School, London SW17 0QT

Correspondence to: Mr Teimory, Worthing Hospital, Lyndhurst Road, Worthing, West Sussex, BN11 2DH.

Accepted for publication 7 May 1998

AIM---To investigate the possible association between the use of three piece foldable silicone polypropylene (SPP) intraocular lenses (IOLs) and an increased risk of postoperative endophthalmitis.
METHODS---A retrospective analysis was conducted of all cases of postoperative endophthalmitis following phacoemulsification surgery in a single unit over a 3 year period. The incidence of postoperative endophthalmitis in eyes with SPP IOLs was compared with the incidence in eyes with single piece polymethylmethacrylate (PMMA) IOLs.
RESULTS---772 cataract extractions by phacoemulsification were performed. One (0.16%) of the 622 patients with PMMA IOLs developed endophthalmitis. Excluding one patient who had aplastic anaemia, five (3.33%) of 150 patients with SPP IOLs developed endophthalmitis. The relative risk for postoperative endophthalmitis associated with the use of the SPP IOL compared with the PMMA IOL was 20.1 (p=0.015).
CONCLUSION---This study adds further evidence to the concept that SPP IOLs can be a significant risk factor in the development of postoperative endophthamitis.

Keywords: cataract surgery; phacoemulsification; intraocular lenses; endophthalmitis


© 1998 by British Journal of Ophthalmology



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